Effects of citrus flavonoids, 5-hydroxy-3,6,7,8,3′,4′-hexamethoxyflavone and 3,5,6,7,8,3′,4′-heptamethoxyflavone, on the activities of macrophage scavenger receptors and the hepatic LDL receptor
Epidemiological and animal studies point to a possible protective effect of citrus flavonoids against cardiovascular diseases. The aim of this study is to investigate the effects of citrus flavonoids, 5-hydroxy-3,6,7,8,3′,4′-hexamethoxyflavone (5-OH-HxMF) and 3,5,6,7,8,3′,4′-heptamethoxyflavone (HpMF), on th
In terminally differentiated THP-1 macrophages, 5-OH-HxMF and HpMF could ... 5-OH-HxMF (10–20 μM) enhanced DiI-LDL uptake by 1.33-fold due to the enhanced LDLR expression. ... C. Li , F. B. Kraemer , T. E. Ahlborn and J. Liu , J. Biol.